Finding and Drugging the Vulnerabilities of RAS-Dependent Cancers
نویسنده
چکیده
Kinase inhibitors have ushered in the era of targeted therapy, but their utility to date is primarily limited to cancers bearing oncogenic kinase mutations. Two papers in this issue (Luo et al., 2009; Scholl et al., 2009) could change this landscape by uncovering kinase-specific vulnerabilities in tumors with RAS mutations.
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عنوان ژورنال:
- Cell
دوره 137 شماره
صفحات -
تاریخ انتشار 2009